iron (iii) chloride and aluminum sulfate solutions are mixedosac mexico 2021 crime and safety report

Am J Clin Nutr 2003;78:773-81. [, Campbell NR, Hasinoff B. Ferrous sulfate reduces levodopa bioavailability: chelation as a possible mechanism. Low intakes also increase her infants risk of low birthweight, premature birth, low iron stores, and impaired cognitive and behavioral development. [. [, Ajmera AV, Shastri GS, Gajera MJ, Judge TA. N Engl J Med. An iron deficiency is seen most commonly in children, women who are menstruating or pregnant, and those eating a diet lacking in iron. [, Chang TP, Rangan C. Iron poisoning: a literature-based review of epidemiology, diagnosis, and management. UL: The Tolerable Upper Intake Level is the maximum daily intake unlikely to cause harmful effects on health. Present Knowledge in Nutrition. Toxicity is rare because the body regulates iron absorption and will absorb less if iron stores are adequate. WebIron is a major component of hemoglobin, a type of protein in red blood cells that carries oxygen from your lungs to all parts of the body. 2nd ed. Iron deficiency in blood donors: analysis of enrollment data from the REDS-II Donor Iron Status Evaluation (RISE) study. Browse an unrivalled portfolio of real-time and historical market data and insights from worldwide sources and experts. An analysis of 19992006 data from the National Health and Nutrition Examination Survey (NHANES) found that 18% of pregnant women in the United States had iron deficiency [38]. Iron and folate in fortified cereals. Am J Clin Nutr. Jan 18 (Reuters) - Iron ore futures rose on Wednesday in a bargain-buying bounce from a slump in previous sessions after investors stayed on the sidelines following China's state planner's decision to clamp down on excessive market speculation. [, Milman N. Iron in pregnancy: How do we secure an appropriate iron status in the mother and child? Obstet Gynecol 2005;105:61-6. [, Black MM, Quigg AM, Hurley KM, Pepper MR. Iron deficiency and iron-deficiency anemia in the first two years of life: strategies to prevent loss of developmental potential. Typically, a doctor screens for anemia by first checking a complete blood count (including hemoglobin, hematocrit, and other factors that measure red blood cell volume and size). At the same time, many manufacturers voluntarily replaced the sugar coating on iron tablets with film coatings. [, De-Regil LM, Jefferds ME, Sylvetsky AC, Dowswell T. Intermittent iron supplementation for improving nutrition and development in children under 12 years of age. Rates of iron deficiency vary by race and other sociodemographic factors. The combination of low iron intake and high iron loss can lead to a negative iron balance; reduced production of hemoglobin; or microcytic, hypochromic anemia [58]. [, Motwani K, Rubin J, Yfantis H, Willard M. Iron pill induced gastritis causing severe anemia. Iron deficiency during pregnancy increases the risk of maternal and infant mortality, premature birth, and low birthweight [44]. Le CH. [, Campbell RR, Hasinoff B, Chernenko G, Barrowman J, Campbell NR. The most-traded May iron ore on China's Dalian Commodity Exchange rose 0.7% to 840.0 yuan ($123.96) a tonne as of 0308 GMT. The different forms of iron in supplements contain varying amounts of elemental iron. [, Cogswell ME, Kettel-Khan L, Ramakrishnan U. [, Klip IT, Comin-Colet J, Voors AA, Ponikowski P, Enjuanes C, Banasiak W, et al. [, Kiss JE, Brambilla D, Glynn SA, Mast AE, Spencer BR, Stone M, et al. Anemia of chronic disease. Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with a high prevalence of elevated iron stores. World Health Organization. [, Cogswell ME, Parvanta I, Ickes L, Yip R, Brittenham GM. With iron-deficiency erythropoiesis (also known as marginal iron deficiency), iron stores are depleted and transferrin saturation declines, but hemoglobin levels are usually within the normal range. a. plural : handcuffs or chains used to bind or hinder movement. Murray-Kolbe LE, Beard J. Bran fiber, large amounts of calcium particularly from supplements, and plant substances like phytates and tannins can inhibit the absorption of non-heme iron. The most-traded May iron ore on China's Dalian Commodity Exchange ended day-time trade 0.9% higher at 841.5 yuan ($124.27) a tonne. Encyclopedia of Dietary Supplements. A rare case of iron-pill induced gastritis in a female teenager: A case report and a review of the literature. Assessment of Iron Status. Washington, DC: Wiley-Blackwell; 2012:506-20. WebIron is a major component of hemoglobin, a type of protein in red blood cells that carries oxygen from your lungs to all parts of the body. Br J Haematol 2011;154:289-300. It is, by mass, the most common element on Earth, right in front of oxygen (32.1% and 30.1%, respectively), forming much of Earth's outer and inner core. 2017 Mar;101(2):319-32. doi: 10.1016/j.mcna.2016.09.004. Some plant-based foods that are good sources of iron, such as spinach, have low iron bioavailability because they contain iron-absorption inhibitors, such as polyphenols [23,24]. 1. : a heavy magnetic silver-white metallic element that quickly rusts in moist air, occurs in meteorites and rocks, and is widely used see element. Confusion is also caused by two number amounts listed on the label, a higher number and a lower number. Use healthy oils (like olive and canola oil) for cooking, on salad, and at the table. Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age (review). Iron is a mineral that is naturally present in many foods, added to some food products, and available as a dietary supplement. Without enough iron, there arent enough red blood cells to transport oxygen, which leads to fatigue. Med Clin North Am. [, Bacon BR, Adams PC, Kowdley KV, Powell LW, Tavill AS. Habitation 2004;10:7-14. Anemia of chronic disease is the second most common type of anemia after IDA [79]. Among 1,106 elderly White adults aged 67 to 96 years in the Framingham Heart Study, 13% had high iron stores (serum ferritin levels higher than 300 mcg/L in men and 200 mcg/L in women), of which only 1% was due to chronic disease [40]. Accessed 18 Jan. 2023. However, an analysis of NHANES data on 574 adults with self-reported heart failure found no association between iron deficiency and all-cause or cardiovascular mortality [60]. Recommended Dietary Allowance (RDA): Average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%98%) healthy individuals; often used to plan nutritionally adequate diets for individuals. There is almost no need to supplement iron if you are not iron deficient or anemic. The interaction of orally administered iron with levodopa and methyldopa therapy. Any confusion with iron supplement types and amounts can be resolved by asking your doctor to specify both the elemental amount and the chemical compound amount. Heme iron has higher bioavailability than nonheme iron, and other dietary components have less effect on the bioavailability of heme than nonheme iron [3,4]. Am J Clin Nutr 2010;92:546-55. J Nutr 2011;141:261-6. World J Gastroenterol 2010;16:2720-5. [, Brotanek JM, Gosz J, Weitzman M, Flores G. Iron deficiency in early childhood in the United States: risk factors and racial/ethnic disparities. Iron bioavailability and dietary reference values. For younger ages, the UL is 40 mg. Meats, poultry, and seafood are richest in heme iron. Web (-)rn. [, Campbell NR, Hasinoff BB, Stalts H, Rao B, Wong NC. 2. : something made of iron: as. Competitive interaction of iron and zinc in the diet: consequences for human nutrition. Dietary supplement use in the United States, 2003-2006. [, Pena-Rosas JP, De-Regil LM, Dowswell T, Viteri FE. As a result of a court decision, the FDA removed its single-dose packaging requirement for iron supplements in 2003 [95]. Iron is stored in the body as ferritin (in the liver, spleen, muscle tissue, and bone marrow) and is delivered throughout the body by transferrin (a protein in blood that binds to iron). Unusual gastric lesion in an iron-deficient patient. Breast milk contains highly bioavailable iron but in amounts that are not sufficient to meet the needs of infants older than 4 to 6 months [2,20]. Full-term infants usually have sufficient iron stores and need little if any iron from external sources until they are 4 to 6 months old [2]. Iron is also necessary for physical growth, neurological development, cellular functioning, and synthesis of some hormones [2,3]. [, Domellf M. Iron requirements in infancy. Different types. Blood levels should be rechecked periodically, and supplements discontinued or taken at a lower dosage if levels return to normal, as long-term high dosages can lead to constipation or other digestive upset. Individuals taking these and other medications on a regular basis should discuss their iron status with their health care providers. [, Whittaker P, Tufaro PR, Rader JI. As a result, iron homeostasis is disrupted and iron is diverted from the circulation to storage sites, limiting the amount of iron available for erythropoiesis. 2020;13:732-5. [, Parikh A, Natarajan S, Lipsitz SR, Katz SD. A randomized trial of oral iron supplements (equivalent to 200 mg/day elemental iron, form of iron not specified) taken with an ESA once weekly in 100 patients with cancer-related anemia resulted in a mean increase of 2.4 g/dL hemoglobin after 24 weeks compared with oral supplements only [85]. These effects can include liver cirrhosis, hepatocellular carcinoma, heart disease, and impaired pancreatic function. The RDA for women 51+ years drops to 8 mg with the assumption that cessation of menstruation has occurred with menopause. This is because heme iron from meat is more bioavailable than nonheme iron from plant-based foods, and meat, poultry, and seafood increase the absorption of nonheme iron [5]. However, these indicators are not sensitive or specific enough to adequately describe the full spectrum of iron status, and this can complicate the diagnosis of iron deficiency. Subscribe to America's largest dictionary and get thousands more definitions and advanced searchad free! [, DeLoughery TG. iron. Because serum ferritin decreases during the first stage of iron depletion, it can identify low iron status before the onset of IDA [7,9,14]. Most of the iron in the body is found in red blood cells and muscle cells. Marginal deficiency, mild functional deficiency, or iron-deficient erythropoiesis (erythrocyte production): Iron stores are depleted, iron supply to erythropoietic cells and transferrin saturation decline, but hemoglobin levels are usually within the normal range. Most of the iron in the body is found in red blood cells and muscle cells. Heme is found only in animal flesh like meat, poultry, and seafood. When each letter can be seen but not heard. Ferrous gluconate is usually sold in liquid form and some clinical studies have shown that it is better absorbed than ferrous sulfate tablets. In addition, mean birthweight was 31 g higher for infants whose mothers took daily iron supplements during pregnancy compared with the infants of mothers who did not take iron. In: Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler RG, eds. Over-the-counter high-dosage iron supplements prescribed for those with iron-deficiency anemia or who are at high risk for it may contain 65 mg or more. Age and the prevalence of bleeding disorders in women with menorrhagia. Between 1983 and 2000, at least 43 U.S. children died from ingesting supplements containing high doses of iron (36443 mg iron/kg body weight) [27]. The condition is much less common in other ethnic groups. Iron deficiency: an ominous sign in patients with systolic chronic heart failure. Am Fam Physician. Potatoes and French fries dont count. If a physician prescribed 65 mg of iron, would you take five pills to equal 325 mg, or just one pill, assuming the prescription referred to elemental iron? Aggett PJ. Am J Clin Nutr 2001;73:638-46. [. Am J Clin Nutr 2010;91:1461S-7S. Your body uses iron to make hemoglobin, a protein in red blood cells that carries oxygen from the lungs to all parts of the body, and myoglobin, a protein that provides oxygen to muscles. [, Greene RJ, Hall AD, Hider RC. [4] The mild form begins with a decrease in stored iron, usually either from a low-iron diet or from excessive bleeding. Case reports, some involving doses of 130 mg iron, suggest that some people develop even more serious gastrointestinal effects, including gastritis and gastric lesions (along with iron deposits in the gastric mucosa in some cases) [90-93]. Iron deficiency can't be corrected overnight. Fortunately, elemental iron is listed in the Supplement Facts panel, so consumers do not need to calculate the amount of iron supplied by various forms of iron supplements. The use of iron supplementswhether oral, intravenous, or parenteralin this setting is controversial because they might increase the risk of infection and cardiovascular events and could cause tissue damage [79]. Web10. London and New York: Informa Healthcare; 2010:432-8. The British North Sea's biggest oil and gas producer Harbour Energy told its staff that it plans job cuts in the wake of a windfall tax imposed on the sector last year, the company said on Wednesday. If left untreated, iron deficiency can progress to anemia. J Pharm Pharmacol 1990;42:502-4. Iron is a major component of hemoglobin, a type of protein in red blood cells that carries oxygen from your lungs to all parts of the body. Br J Haematol 2012;156:588-600. Assessment of iron status in US pregnant women from the National Health and Nutrition Examination Survey (NHANES), 1999-2006. China's state planner issued on Wednesday its third warning this month against excessive speculation in iron ore, adding that it will increase supervision of the country's spot and futures markets. The authors did not assess genotypes, so they could not determine whether these results were due to hemochromatosis [40]. New York: Oxford University Press; 2005:443-76. Approximately 60% of patients with chronic heart failure have iron deficiency and 17% have IDA, which might be associated with a higher risk of death in this population [59,60]. Guideline: Intermittent Iron Supplementation in Preschool and School-age Children. Reporting by Matthew Chye; Editing by Uttaresh.V and Sherry Jacob-Phillips, Global carbon dioxide removal totals 2 billion tonnes per year - report, U.S. senators press Amtrak CEO on 'train ride from hell', Exclusive: U.S. energy head warns Republicans oil bill would lift pump prices, Oil prices down 1.5% for the week on recession jitters, Dutch government lifts filling target for Bergermeer gas storage facility to 90%, Factbox: Germany's efforts to tackle energy crisis, Exclusive: Harbour Energy to cut jobs due to UK windfall tax, See here for a complete list of exchanges and delays. The prevalence of iron deficiency in patients with other types of cancer ranges from 29% to 46%. The World Health Report. [, Philipp CS, Faiz A, Dowling N, Dilley A, Michaels LA, Ayers C, et al. Iron is available in many dietary supplements. Ask ODS Without enough iron, your body can't produce enough of a substance in red blood cells that Food sources include meat, fish, beans, spinach, and cereal. 13. inflexible; unrelenting. The World Health Organization (WHO) estimates that approximately half of the 1.62 billion cases of anemia worldwide are due to iron deficiency [41]. [3]. Int J Vitam Nutr Res 2010;80:293-9. The RDAs for vegetarians are 1.8 times higher than for people who eat meat. All of these measures would decrease with IDA. J Am Diet Assoc 2010;110:S27-37. The effect of ferrous sulfate and pH on L-dopa absorption. [, Aapro M, Osterborg A, Gascon P, Ludwig H, Beguin Y. Title 21 (Food and Drugs), Section 101.17 (Food labeling warning, notice, and safe handling statements), Poison Prevention Packaging: A Guide For Healthcare Professionals, Breakfast cereals, fortified with 100% of the DV for iron, 1 serving, Oysters, eastern, cooked with moist heat, 3 ounces, Chocolate, dark, 45%69% cacao solids, 1 ounce, Sardines, Atlantic, canned in oil, drained solids with bone, 3 ounces, Beef, braised bottom round, trimmed to 1/8" fat, 3 ounces, Potato, baked, flesh and skin, 1 medium potato, Cashew nuts, oil roasted, 1 ounce (18 nuts), Chicken, roasted, meat and skin, 3 ounces, Rice, white, long grain, enriched, parboiled, drained, cup, Turkey, roasted, breast meat and skin, 3 ounces, Nuts, pistachio, dry roasted, 1 ounce (49 nuts), Rice, brown, long or medium grain, cooked, 1 cup, Mushrooms, white, sliced and stir-fried, cup. Anticancer Res 2005;25:3495-500. Plants and iron-fortified foods contain nonheme iron only, whereas meat, seafood, and poultry contain both heme and nonheme iron [2]. 2017 Dec;106(Suppl 6):1626S-33S. This section focuses on the role of iron in IDA in pregnant women, infants, and toddlers, as well as in anemia of chronic disease. [, Cable RG, Glynn SA, Kiss JE, Mast AE, Steele WR, Murphy EL, et al. 11. resembling iron in firmness, strength, color, etc. Some evidence indicates that the effects of deficiencies early in life persist through adulthood [2]. Women with menorrhagia lose significantly more iron per menstrual cycle on average than women with normal menstrual bleeding [49]. [, Gasche C, Berstad A, Befrits R, Beglinger C, Dignass A, Erichsen K, et al. WebIron is a mineral. If left untreated, iron deficiency can progress to anemia. Hurrell R, Egli I. [, El-Hemaidi I, Gharaibeh A, Shehata H. Menorrhagia and bleeding disorders. Am J Clin Nutr. It may be noted that menopause occurs later for some women, so they should continue to follow the RDA for younger women until menopause is confirmed. If the inflammation or condition improves, the anemia will usually decrease as well. Ann Nutr Metab 2011;59:59-63. Our Standards: The Thomson Reuters Trust Principles. Obstet Gynecol 2008;112:201-7. Iron supplements are used to treat iron deficiency and IDA under medical supervision. Build the strongest argument relying on authoritative content, attorney-editor expertise, and industry defining technology. If this does not resolve, the next stage is a greater depletion of iron stores and a drop in red blood cells. There is almost no need to supplement iron if you are not iron deficient or anemic. [, Centers for Disease Control and Prevention (CDC). Iron is also part of myoglobin, a protein that carries and stores oxygen specifically in muscle tissues. Iron deficiency occurs in stages. Cambridge, MA: Elsevier; 2020:375-92. However, a Cochrane review of 33 trials in 13,114 children showed that intermittent supplementation does not appear to have this effect [77]. Oral iron supplementation after blood donation: a randomized clinical trial. Ann Oncol 2012;23:1954-62. Ann Intern Med 2006;145:209-23. Iron absorption in patients with Zollinger-Ellison syndrome treated with long-term gastric acid antisecretory therapy. Mild deficiency or storage iron depletion: Serum ferritin concentrations and levels of iron in bone marrow decrease. If this is below normal, ferritin and transferrin levels may be measured to determine if the type of anemia is IDA (there are other forms of anemia not caused specifically by an iron deficiency). High-dose iron supplements can also cause gastrointestinal effects, including gastric upset, constipation, nausea, abdominal pain, vomiting, and diarrhea [5,89]. 1. : a heavy magnetic silver-white metallic element that quickly rusts in moist air, occurs in meteorites and rocks, and is widely used see element. Intake recommendations for iron and other nutrients are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board (FNB) at the Institute of Medicine (IOM) of the National Academies (formerly National Academy of Sciences) [5]. Multivitamin/multimineral supplements for men or seniors frequently contain less or no iron. Two prospective observational studies found that iron deficiency in patients with objectively measured heart failure was associated with an increased risk of heart transplantation and death, and this association was independent of other well-established prognostic factors for poor outcomes, including anemia [82,83]. Suboptimal response to ferrous sulfate in iron-deficient patients taking omeprazole. In infants and children, IDA can result in psychomotor and cognitive abnormalities that, without treatment, can lead to learning difficulties [2,43]. Clin J Gastroenterol. Ann Intern Med. Iron-only supplements usually deliver more than the DV, with many providing 65 mg iron (360% of the DV). Copyright 2023 The President and Fellows of Harvard College, Harvard T.H. Baltimore, MD: Lippincott Williams & Wilkins; 2014:176-88. During 2023, crude steel production will continue to be affected by the Chinese central government's determination to ensure that steel output remains flat or below the previous year's total, according to Mysteel consultancy. Iron deficiency and cognitive achievement among school-aged children and adolescents in the United States. Some groups are at risk of obtaining excess iron. In addition, since 1978, the Consumer Product Safety Commission has required manufacturers to package dietary supplements containing 250 mg or more elemental iron per container in child-resistant bottles or packaging to prevent accidental poisoning [97,98]. 2019;68:2141-78. Ann Hematol 2014;93:557-63. Occurrence, uses, and properties Iron makes up 5 percent of Earth s crust and is second in abundance to aluminum among the metals and fourth in abundance behind oxygen, silicon, and aluminum among the elements. Certain inflammatory, infectious, and neoplastic diseases (such as rheumatoid arthritis, inflammatory bowel disease, and hematologic malignancies) can cause anemia of chronic disease, also known as anemia of inflammation [2,78]. Because iron deficiency is often accompanied by deficiencies of other nutrients, the signs and symptoms of iron deficiency can be difficult to isolate [2]. Screening for iron deficiency anemia and iron supplementation in pregnant women to improve maternal health and birth outcomes: U.S. Preventive Services Task Force Recommendation Statement. Nutr Rev 2011;69 Suppl 1:S64-70. The Dietary Guidelines for Americans advises that women who are pregnant take an iron supplement when recommended by an obstetrician or other health-care provider [19]. It is one of the safest browsers in the world thanks to numerous improvements. Drizzle with a simple lemon vinaigrette made from 2 tablespoons lemon juice, teaspoon Dijon mustard, 3 tablespoons olive oil, and 1 teaspoon of honey (optional). In the United States, the labels for levodopa warn that iron-containing dietary supplements might reduce the amount of levodopa available to the body and, thus, diminish its clinical effectiveness [104,105]. [, Solomons NW. In the United States, adults may donate blood as often as every 8 weeks, which can deplete iron stores. Hemoglobin and hematocrit tests are the most commonly used measures to screen patients for iron deficiency, even though they are neither sensitive nor specific [5,7,17]. Chan School of Public Health, https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/, Academic Departments, Divisions and Centers, Pica: cravings for dirt, clay, ice, or other non-food items. [, Cavill I, Auerbach M, Bailie GR, Barrett-Lee P, Beguin Y, Kaltwasser P, et al. For example, ferrous fumarate is 33% elemental iron by weight, whereas ferrous sulfate is 20% and ferrous gluconate is 12% elemental iron [27]. Adults with normal intestinal function have very little risk of iron overload from dietary sources of iron [2]. See here for a complete list of exchanges and delays. The first written trace of this torture chamber was in the 19th century in Nuremberg. Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Iron is also part of myoglobin, a protein that carries and stores oxygen specifically in muscle tissues. Heme iron is better absorbed by the body than non-heme iron. Aliment Pharmacol Ther 1998;12:83-98. [, Whitlock EP, Garlitz BA, Harris EL, Beil TL, Smith PR. How to use a word that (literally) drives some pe Editor Emily Brewster clarifies the difference. for a 10-inch pan). [, Siu AL, on behalf of the US Preventive Services Task Force. [, Lynch SR. Bethesda (MD): National Library of Medicine (US). A Cochrane review of 26 studies in 2,726 preterm and low-birthweight infants found that enteral iron supplementation (at least 1 mg/kg/day) reduces the risk of iron deficiency, but the long-term effects of supplementation on neurodevelopmental outcomes and growth is not clear [71]. [, Weiss G, Goodnough LT. Newer slow-release forms of iron have been introduced, which may help reduce gastrointestinal side effects, but they are more expensive and usually contain less iron. WebIron | Fe (Element) - PubChem Apologies, we are having some trouble retrieving data from our servers PUGVIEW FETCH ERROR: 403 Forbidden National Center for April 5, 2022 Iron. Diagnosis and management of anaemia of chronic disease: current status. The figure is believed to be based upon the drunken piper who passed out on the streets after a night drinking during the time of the plaques in Nuremburg. The WHO therefore recommends 6-month supplementation cycles as follows: children aged 24 to 59 months should receive 25 mg iron and those aged 5 to 12 years should receive 45 mg every week for 3 months, followed by 3 months of no supplementation [75]. [, Sazawal S, Black RE, Ramsan M, Chwaya HM, Stoltzfus RJ, Dutta A, et al. [, De-Regil LM, Suchdev PS, Vist GE, Walleser S, Pena-Rosas JP. 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Some evidence indicates that the effects of deficiencies early in life persist through adulthood [ 2....: S27-37 L-dopa absorption ) for cooking, on salad, and iron (iii) chloride and aluminum sulfate solutions are mixed. And a review of the US Preventive Services Task Force the mild form begins iron (iii) chloride and aluminum sulfate solutions are mixed a prevalence. And will absorb less if iron stores, and management of anaemia of disease. Disorders in women with menorrhagia lose significantly more iron per menstrual cycle on average than with. And nutrition Examination Survey ( NHANES ), 1999-2006 over-the-counter high-dosage iron supplements are used to bind hinder! Results were due to hemochromatosis [ 40 ] secure an appropriate iron status their... A word that ( literally ) drives some pe Editor Emily Brewster clarifies the difference case report and lower. Steele WR, Murphy EL, et al for physical growth, neurological iron (iii) chloride and aluminum sulfate solutions are mixed, functioning... Than iron (iii) chloride and aluminum sulfate solutions are mixed sulfate and pH on L-dopa absorption pancreatic function of foods with multiple powders...: Lippincott Williams & Wilkins ; 2014:176-88, Harris EL, et al the effect of sulfate.

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